6. Liver Cancer
(Please refer the article on effect of herbotherapy treatment on liver cancer at the bottom of the page)
(3) Risk factors
(5) Diagnosis as per modern science
(6) Staging and grading
(7) Treatment as per Ayurveda (with ayurvedic herbs and
The liver is
a very important organ in the human body. It is placed
under right ribs just under the right lung. The most
important function of the liver is to convert food into
energy and filtering and storing blood. The liver plays a
pivotal role in the detoxification of blood, i.e. removal
of toxins produced in the body due to metabolic activity
of the body. The liver receives blood from two sources,
the hepatic artery supplies the liver with blood from the
heart that is rich in oxygen and the portal vein carries
nutrient rich blood from the digestive organs. Liver also
produces clotting agents necessary for clotting the blood
when the body is injured. It secrets bile into the
intestines, to help absorb nutrients. The liver is made up
of several different types of cells. This is why there are
several types of malignant (cancerous) and benign
(non-cancerous) tumors that can form in the liver.
Hemangioma – The most common type of benign tumor of the
liver, starts in blood vessles. Because most hemangiomas
of the liver cause no symptoms, they do not need
treatment. Some however may need to be surgically removed.
adenomas – These are benign tumors of hepatocytes (the
main type of liver cell). Most cause no symptoms and do
not need treatment. However, some eventually cause
symptoms, such as abdominal pain, a mass in the abdomen,
or blood loss. Because there is a risk that the tumor
could rupture, and a small risk that it would eventually
develop into liver cancer, most experts usually recommend
surgical removal if possible.
nodular hyperplasia – This is a tumor growth of several
cell types. Although FNH tumors are benign, it can be
difficult to tell them apart from true liver cancers, and
they sometimes are surgically removed when diagnosis is
Hepatocellular carcinoma :- It is the most common form of
liver cancer occurring. It is on numerous occasions called
hepatoma because it comes from the hepatocytes. It
accounts for about 75% of primary liver cancers.
Cholangeocarcinomas :- This accounts for 10 to 20% of
primary liver cancers. These are also called intrahepatic
(starting with the liver) Cholangeocarcinomas. These
cancer starts in the small bile ducts within the liver.
Angiosarcomas and hemangiosarcomas: - These are rare
cancers that begin in the blood vessles of the liver.
Exposure to various chemicals such as vinyl chlorides or
thorium oxide, and radioactive elements like radium or
poisons like arsenic are known to cause these types of
cancers. Angiosarcomas grow rapidly, by the time they are
detected the growth is too large to be surgically removed.
Hepatoblastoma: - This is a very rare kind of cancer that
developes in children, usually up to five years of age. If
detected early this cancer is highly treatable.
symptoms in liver cancers are not present until the last
stage when cancer has spread. Many signs and symptoms are
relatively non-specific, they can be caused by other
cancers or non-cancerous diseases. However the following
symptoms may require attention.
Unexplained, unintentional weight loss.
Anorexia – persistent lack of appetite.
enlargement or a mass that can be felt in the area of
Persistent abdominal pain.
Hyperglycemia – Some liver hormones may cause
hyperglycemia ( high blood calcium levels). This can lead
Hypoglycemia – Low blood sugar levels, which can lead to
Gynecomastia – Enlargement of breasts in men, and
shrinking of testis.
– Water retention in the abdominal area. Many patients are
seen with these symptoms.
(i) Gender –
Hepatocellular carcinoma is predominantly more common in
males than in females.
viral hepatitis – Chronic (long term) infection with
hepatitis B virus or Hepatitis C virus is an important
liver cancer risk factor. These infections are responsible
for making liver cancer the most common type of cancer in
Cirrhosis – Cirrhosis is the result of scar tissue
formation in the liver. This can often lead to cancer.
Most liver cirrhosis occurs in people who abuse alcohol.
But, Hepatitis B and C are also major causes of liver
cirrhosis. Another cause is excessive iron in liver.
use – A link has been established between tobacco use and
liver cancer. Combined with alcohol tobacco is very potent
in causing cancer.
Inherited metabolic diseases – Certain metabolic diseases
can also lead to cirrhosis. People with hemochromatosis,
absorb too much iron from their food. They are more likely
to develop cirrhosis because of the high levels of iron in
Aflatoxins – These cancer causing substances are produced
by a fungus that contaminates crops. Long term exposure
may cause Hepatocellular carcinoma.
Arsenic – Chronic exposure to drinking water contaminated
with naturally occurring arsenic such as that from wells,
increases the risk of liver cancer.
cancer is found in the liver, it did not start there but
spread, or metastasized from a cancer that developed in
the other organs of the body such as pancreas, colon,
stomach, breast, or lung, and metastasized to the liver.
These tumors are named after their primary site of
occurrences and are further known as metastasis. For
example, cancer that started in the lung and spread to the
liver is called metastatic lung cancer with spread to the
following methods are used by modern science in the
diagnsis of liver cancer.
Computed tomography (CT)
Magnetic resonance imaging (MRI)
Alpha-fetoprotein blood test.
(i) Stage 1
– The tumor may be small or large but has not affected
(ii) Stage 2
– There may be many tumors of large size but blood vessles
are not yet affected.
3-a – There are several tumors, and at least one is larger
than 5 cms. And a tumor invades a branch of major liver
blood vessles. (Portal vein or Hepatic vein)
3-b – A tumor invades a nearby organ or a tumor has
penetrated the lining of the liver.
3-c – The cancer has invaded nearby lymph nodes.
(vi) Stage 4
– The cancer has spread to other parts of the body.
Ayurvedic treatment of liver cancer ( Ayurvedic herbs and
Results of 770 patients of
various types of cancer treated at DARF during Jan.2004 to
(1) Total no. of Primary cancer
504. In all 504 patients with primary cancer of various
types were treated at DARF.
patients were rendered disease free
patients were markedly improved
patients were improved
patients were uncured
(2) Total no. of Secondary
(metastases) cancer 266. In all 266 patients with
metastases of different types were treated at DARF.
patients were rendered disease free
patients were markedly improved
patients were improved
patients were uncured
The above results show the high
effectiveness of DARF anti cancer therapy.
(3) Ayurveda Herbs Used in the
cure of liver cancer : -
Effect of herbotherapy treatment of Liver cancer
Shree Shree Maa Anantanand Tirthji
Divyajyot Ayurvedic Research Foundation, `Anantdham',
Paldi Char Rasta, Ahmcdabad 380 007, Gujarat INDIA
Key words: Herbotherapy. LFT, primary and metastatic cancer
Abstract: Cancer is one of the most dangerous diseases: Liver cancer (Malignancies) is a terminal event in many cancers. Herbotherapy is a very effective treatment with no side effects. Citrus medica (Bijoru) is a fruit used since ancient times by the Ayurveda practitioners. Juice of a single bijoru fruit is given to the patients of primary as well as metastatic cancer registered at 'Divyajyot Ayurvedic research Foundation'. It improves patient's liver metabolism, gradually normalizes LFT, prevents recurrence, stops further spread of disease, decreases tumor growth. At the end of 4 to 6 months, patient becomes free from the disease symptoms and leads a normal life.
Liver is the largest gland in the body and performs more than 500 different functions. Primary liver Cancer is relatively rare but metastatic liver cancer (spread from a distant - cancerous organ) is at least 20 times more than primary liver cancer. Liver metastasis is a terminal event in many cancers. Advanced liver metastatic cancer is a significant problem with limited treatment options and has very little chances of survival. Chronic liver diseases includes viral hepatitis, Jaundice,, Alcoholic cirrhosis or primary billiary cirrhosis, hepatitis B, all these are risk factors of hepatocellular carcinoma. Males have higher risk for H CC than females. The metastasis can be either solitary or multiple. In case of multiple metastasis, liver function can become altered, leading to further deterioration in a patient's condition. The treatment options in such a scenario are limited with a usual fatal outcome. Common symptoms found in these patients are hepatomegaly, weight loss, abnormal elevation of liver enzymes, elevation of AFP, Anemia, mass or multiple liver lesions, obstructive jaundice... etc. For the detection of liver carcinoma, elevation of AFP, USG Abdomen, CT scan or MRI of abdomen, needle biopsy or laproscopic liver biopsy is helpful.
100 patients are selected to be screened for " Citrus medica" juice effects on their disease, registered at `Divyajyot Ayurvedic Research Foundation'. The chief of the investigating team and head of the institute "Vaidya Shree Shree Maa Anantanand Tirthaji" and other research committee members, along with their assistant research, doctors and scientist conducted the whole project.
AIMS AND OBJECTIVES:
1. The aim is to study the effects of the juice of the "Citrus medica'", popularly known as "Bijora", in the treatment of patients having primary or metastatic liver cancers with improving liver functions.
2. One of the most "ancient" medical sciences of the world is "Ayurveda". Ayurvedic medicine has no side effects. Since 1978 Vaidya Shree Shree Maa Anantanand Tirdhji treats all types of advanced cancers with different types of anti cancer treatments, somr of them are panchkarma therapy and herbal juice therapy. These treatments find excellent results. The institute is working towards providing the patients with a cure for this terrible disease.
3. To document the data and publish it to enrich the general quantum of medical knowledge.
CRITERIA FOR SELECTION:
All the patients registered at `Divyajyot Ayurvedic Research Foundation' hospital were assessed and selected irrespective of sex, cast creed and age for their present symptoms of abdominal pain, jaundice, hardness of liver side in abdomen, weight loss, loss of appetite. etc... Their clinical investigations at the time of registration prove their site with respect to cancer.
MATERIAL AND METHOD:
Material: Scientific name: Citrus medica L. Common name: Bijoru Family: Rutaceae Useful Parts:Fruit.
Uses: It is used in all kinds of liver diseases, like liver cirrhosis, jaundice, damaged liver. function, viral hepatitis B and C, primary and secondary liver malignancies.
Methods: All patients registered at `Divyajyot Ayurvedic Research Foundation' were given specially prepared treatment.
Their respective findings were analyzed for statistical significance. Patients with liver diseases underwent baseline investigations in the form of liver function test, tumor marker studies, Ultra sound examination of liver and detailed documentation of clinical status. The patient are administered a glass of single Bijora fruit juice in the early morning with empty stomach followed after two hours. This must be continued regularly at least for a minimum period of 3 months.
For the other symptoms patients were advised to take Ayurvedic medicines as per requirement after their prakruti examination and nadi pariksha. The following herbs were administered along with the treatment.
(1) Lindi piper (2) Morepinchh bhasma (3) Kapur kachali churna (4) Tapvadi loh• Kanchnar (5) Bhoamli (6) Vikalo (7) Vayavarno (8) Garmalo (9) Kunvarpathu.
These patients were also advised strict diet restriction like
(1)To stop ghee and oil preparations completely. (2)To avoid spicy food. (3)To take boiled vegetables. (4)To take goat milk. (5)To take papaya and all kinds of citrus fruit.
Their clinical status and biochemical parameters were studied at the interval of 4 to 6 weeks. The course was carried out for at least 3 months. If the juice gives gives positive response it can be increased up to 6 months. After 6 months, radiological investigations were also carried out.
CRITERIA OF ASSESMENT:
(1) All symptoms of liver cancer were reported at the time of patient's registration. The symptoms when reassessed and if improved or scored as symptomatically relief and LFT (Liver Function Test) is encouraging, is considered to be as ` Improved'.
(2) Patient who is observed to be symptomatically normal from disease and LFT is normal and radiological findings are also near about normal, is considered to be 'Markedly Improved'.
(3) Those patients with all investigations like radiological and hematological reports normal, are considered ‘Disease Free’.
(4) Patients with symptoms in status quo or increased are considered to be ` Uncured'.
Total numbers of selected primary cancer patients were 30. Total numbers of selected metastases cancer patients were 70.
Table: 1 Results of primary and metastatic liver cancer patients
Table: 2 Nadi disturbances in primary and metastatic cancer patients
Table: 3 Results of Bijora juice therapy in primary and metastatic liver cancer
Patients with respect to their liver function
Liver Function Test
Improves upto 30%
Improves more than 50%
1 A single Bijora juice early in the morning with empty stomach upto 3 months daily gives very positive results.
2 It improves metabolism, liver function and appetite of the patient.
3 It gradually minimizes the symptoms like nadi dosha, imbalance of prakriti and disturbances in the constitution of patient.
4 It dissolves the tumor gradually.
5 This juice therapy gives rapid results in metastatic cancer than primary cancer.
6 Dwidosh Prakriti is common in primary cancer patients. Metastatic cancer patients have more often a tridosh prakriti.
7 It maintains Hemoglobin level indirectly by gradually improving liver functions.
8 Few patients having advance nature of disease may not be cured.
(Prepared by Divyajyot
Ayurvedic Research foundation India. We are conducting
research and treatment in Ayurvedic herbal cure of
cancer since last 25 years. The data and information
contained on this site is based on Ayurvedic herbal
wisdom and our research.)